Brain Infections Global: An NIHR Global Health Research Group on Improving the Management of Acute Brain Infections
Acute brain infections are major causes of illness and death globally, partly through shortage of expertise in tackling them. In many settings, the causative organisms are not determined because of failures in diagnosis, so that treatment has to be guessed at, and is often wrong.
To tackle this, this GHRG links Liverpool, with its outstanding reputation in brain infections research, to the internationally renowned Warwick Centre for Applied Health Research and Delivery, and to leading research institutes in Malawi, India and Brazil. We are using mixed methods approaches to understand where the difficulties in management lie.
These findings will inform the development of a compound intervention to improve diagnostic investigations. We are also continuing with our recent work strengthening diagnosis through simple diagnostic kits based on pathogen discovery and host genomic approaches. With improved diagnosis, more patients will be on the right treatment, leading to better outcomes.
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This project is funded by the National Institute for Health Research (NIHR) Global Health Research (grant reference number 17/63/110). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care.